Key result
CHF linked to ~328% greater mortality risk in COPD patients, exceeding arrhythmias and acute MI.
Why the study?
COPD is frequently associated with multiple comorbidities that influence prognosis, but the specific association between comorbidities and mortality using a comorbidome approach needed evaluation.
Population
500 patients aged ≥40 years with COPD in Colombia
Comparison
Prevalence and mortality association across various comorbidities
Design
Retrospective cohort study
Authors
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CHF signals heightened mortality risk in COPD; leaves open independence from confounders and requires adjusted prospective validation before practice change.**[[1]](https://www.mdpi.com/2077-0383/15/9/3365)[[2]](https://www.researchgate.
Cohort (n=500)
No
Effect estimate: OR 4.28 (95% CI 2.55-7.18)
Gómez et al. (2026) conducted a cohort in Chronic Obstructive Pulmonary Disease (COPD) (n=500). Comorbidities (e.g., congestive heart failure) was evaluated on Mortality (OR 4.28, 95% CI 2.55-7.18). Congestive heart failure was the comorbidity most strongly associated with mortality in COPD patients (OR 4.28; 95% CI 2.55-7.18), followed by arrhythmias and acute myocardial infarction.
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