Why the study?
Does shorter DAPT reduce major bleeding compared to standard DAPT in patients with acute coronary syndrome treated with new generation stents?
Does shorter DAPT reduce major bleeding compared to standard DAPT in patients with acute coronary syndrome treated with new generation stents?
In patients with acute coronary syndrome receiving new generation stents, a shorter duration of DAPT reduces major bleeding without compromising ischemic or mortality outcomes.
Supports shorter DAPT to reduce bleeding in ACS with new stents; reinforces RCT evidence on ischemic and mortality safety.
In patients with acute coronary syndrome treated with new generation stents, the shorter DAPT leads to a marked reduction in the risk of major bleeding compared with the standard DAPT. This benefit is achieved without increasing the risk of mortality or ischemic outcomes. The study protocol was registered in PROSPERO (CRD42020189871).
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Zhang et al. (2021) studied this question.
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