November 20, 2013JAMA

Outcomes Following Transcatheter Aortic Valve Replacement in the United States

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Structured PICO

Population

7,710 patients undergoing transcatheter aortic valve replacement (TAVR) for severe, symptomatic aortic stenosis (20% inoperable, 80% high-risk but operable), median age 84, 49% women, across 224 US hospitals.

Intervention

Transcatheter aortic valve replacement (TAVR) using the Edwards Sapien XT device

Outcome

All-cause in-hospital mortality and stroke following TAVRhard clinical

Initial US commercial experience with TAVR demonstrated high device implantation success (92%) and acceptable in-hospital mortality (5.5%) and stroke (2.0%) rates in high-risk and inoperable patients.

Discussion

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Implication

Supports TAVR use in high-risk patients; extends trial data to commercial practice but leaves comparative outcomes open.

Cite This Study

Mack et al. (2013) studied this question.

synapsesocial.com/papers/69f53fedb76c9a4576d8d1aa https://doi.org/10.1001/jama.2013.282043

Topics

Valvular heart disease Congenital heart disease adults

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Outcomes Following Transcatheter Aortic Valve Replacement in the United States

Structured PICO

Discussion

Implication

Cite This Study

Topics

Outcomes Following Transcatheter Aortic Valve Replacement in the United States

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider