Review summarizes clinical features and treatment options for Terrien’s marginal degeneration, highlighting diagnosis challenges.
Terrien's marginal degeneration is a rare idiopathic condition characterized by minimally symptomatic, typically bilateral peripheral corneal thinning without ulceration, accompanied by superficial neovascularization and lipid deposition. The absence of pathognomonic diagnostic criteria, along with the diversity of clinical manifestations and potential complications, can make establishing the diagnosis more difficult. This review summarizes current knowledge regarding the etiopathogenesis, clinical course, and diagnostic features of Terrien's marginal degeneration. It also discusses contemporary classifications and current approaches to differential diagnosis and treatment of the disease.
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Krakhmaleva et al. (2026) studied this question.
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