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April 28, 2026PLoS PathogensOpen Access

Correction: Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

Anna Bachmann Ellen Bruske Ralf Krumkamp Louise Turner J Stephan Wichers Michaela Petter Jana Held Michael F Duffy B Kim Lee Sim Stephen L Hoffman Peter G Kremsner Bertrand Lell Thomas Lavstsen Matthias Frank Benjamin Mordmüller Egbert Tannich

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Key Points

The aim is to investigate how naturally acquired immunity affects the expression of virulence genes in malaria.
Conducted controlled human malaria infections using Plasmodium falciparum.
Analyzed the expression of virulence genes in relation to levels of acquired immunity.
Demonstrated that naturally acquired immunity significantly influences virulence gene expression.
Showed varying levels of gene expression based on the immune status of participants.

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Implication

Correction highlights the effect of naturally acquired immunity on virulence in malaria infections.

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Cite This Study

Bachmann et al. (2026) studied this question.

synapsesocial.com/papers/69f593f271405d493affec8d https://doi.org/10.1371/journal.ppat.1014177

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