Key result
CT perfusion lesion volume predicts stroke recurrence with ~88% sensitivity.
Why the study?
Does the volume of time to maximum concentration >4 s on computed tomography perfusion predict stroke recurrence in patients with symptomatic non-acute atherosclerotic middle cerebral artery occlusion?
Cohort
Does the volume of time to maximum concentration >4 s on computed tomography perfusion predict stroke recurrence in patients with symptomatic non-acute atherosclerotic middle cerebral artery occlusion?
p-value: p=< 0.001
Volume of time to maximum concentration >4 s on computed tomography perfusion can be used to predict stroke recurrence in patients with symptomatic non-acute atherosclerotic middle cerebral artery occlusion.
< 0.001, sensitivity = 0.88 and specificity = 0.65).ConclusionsThe risk of stroke recurrence in patients with symptomatic non-acute atherosclerotic middle cerebral artery occlusion gradually increases with the volume of time to maximum concentration >4 s. Patients with volume of time to maximum concentration >4 s larger than 99.8 mL may have a significantly higher risk of stroke. Volume of time to maximum concentration >4 s on computed tomography perfusion can be used to predict the prognosis in patients with symptomatic non-acute atherosclerotic middle cerebral artery occlusion.
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Zhang et al. (2026) conducted a cohort in symptomatic non-acute atherosclerotic middle cerebral artery occlusion. Volume of time to maximum concentration >4 s on computed tomography perfusion was evaluated on stroke recurrence (p=< 0.001). A volume of time to maximum concentration >4 s larger than 99.8 mL on CT perfusion predicted stroke recurrence with a sensitivity of 0.88 and specificity of 0.65 (P<0.001).
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