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May 2, 2026

The importance of meeting physical activity recommendations and limiting sedentary time in adult survivors of childhood acute lymphoblastic leukemia - associations with fatigue and HRQoL.

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Authors

LJLaura JessRoyal Hospital for ChildrenKAKatarina AiliHalmstad UniversityJNJens NygrenHalmstad University

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Implication

Cross-sectional study finds physical activity impact quality of life and fatigue in adult survivors of childhood ALL, suggesting promotion is beneficial.

Key Points

  • Investigating the relationship between physical activity levels, sedentary time, fatigue, and health-related quality of life among adult survivors of childhood acute lymphoblastic leukemia.
  • National cross-sectional study including 426 adult survivors of childhood ALL from 1985-2007.
  • Participants completed questionnaires on physical activity, sedentary time, fatigue, and HRQoL.
  • Associations analyzed using linear regression.
  • 44% of participants did not meet physical activity recommendations.
  • Not meeting recommendations linked to greater fatigue (MFI-20 β = 1.7, p = 0.033) and lower HRQoL (SF-36 PCS β = -3.3, p < 0.001; SF-36 MCS β = -4.2, p < 0.001).
  • Sedentary time ≥ 7 h/day associated with lower mental HRQoL (SF-36 MCS β = -3.6, p = 0.003).

Cite This Study

Jess et al. (2026) studied this question.

synapsesocial.com/papers/69f594b171405d493afff7bfhttps://doi.org/10.1007/s11764-026-02027-z
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Physical Inactivity in Adult Survivors of Childhood Acute Lymphoblastic Leukemia: A Report from the Childhood Cancer Survivor Study2007 · 219 citations
  2. 2Physical Activity and Sedentary Behaviors in Childhood Acute Lymphoblastic Leukemia Survivors2019 · 25 citations
  3. 3Sedentary behavior and physical activity in survivors of childhood hodgkin lymphoma: a cross-sectional study2026
  4. 4Associations between leisure‐time physical activity and health‐related quality of life among adolescent and adult survivors of childhood cancers2009 · 105 citations
  5. 5Prevention of Long-term Adverse Health Outcomes With Cardiorespiratory Fitness and Physical Activity in Childhood Acute Lymphoblastic Leukemia Survivors2019 · 52 citations