Why the study?
Most childhood acute lymphoblastic leukemia survivors develop chronic treatment-related adverse effects, but the association of cardiorespiratory fitness or adherence to physical activity guidelines with major long-term health outcomes required evaluation.
Does good cardiorespiratory fitness and physical activity prevent long-term adverse health outcomes in childhood ALL survivors?
Population
247 childhood ALL survivors
Comparison
Good cardiorespiratory fitness or adherence to physical activity guidelines vs lower levels
Design
Cohort study
Authors
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Good CRF/PA linked to fewer adverse outcomes in ALL survivors; leaves open whether interventions improve long-term health.
Does good cardiorespiratory fitness and physical activity prevent long-term adverse health outcomes in childhood ALL survivors?
Higher cardiorespiratory fitness and physical activity levels are associated with a lower prevalence of late adverse health effects, including obesity and depression, in childhood ALL survivors.
LeMay et al. (2019) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: