Key result
Mitral annular calcification progresses to clinically significant valvular disease in ~8% of affected patients.
Mitral annular calcification is a common degenerative process associated with aging and cardiovascular risk factors that can lead to clinically significant valvular disease and complicates valvular interventions.
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Prompts vigilance for MAC in elderly cardiac patients; leaves open predictors of progression to clinically significant valvular disease.
Oprysko et al. (2026) conducted a review in Mitral annular calcification. Mitral annular calcification has a general population prevalence of 8-15%, with 8% of affected patients developing clinically significant valvular disease such as mitral stenosis or regurgitation.
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