What question did this study set out to answer?

May 4, 2012Circulation Heart FailureOpen Access

Lifetime Analysis of Hospitalizations and Survival of Patients Newly Admitted With Heart Failure

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Why the study?

What are the predictors of hospitalization and patterns of cardiovascular events over the lifetime of patients newly admitted with heart failure?

Population

8543 newly discharged patients with heart failure in the Enhanced Feedback For Effective Cardiac Treatment…

Design

Cohort

Follow-up

10-year

Authors

SCSoohun ChunUniversity of Toronto JTJack V. TuHeart Failure & Transplant HWHarindra C. WijeysunderaInterventional / Structural Cardiology

Discussion

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Implication

Ischemic HF may warrant closer postdischarge surveillance; leaves open whether etiology-specific strategies reduce recurrent events.

Key Points

This analysis aims to identify predictors of hospitalization and patterns of cardiovascular events in heart failure patients over their lifetime.
Examined recurrent hospitalizations and cardiovascular events among 8543 newly discharged heart failure patients over 10 years.
Analyzed data from April 1999 to March 2001 with a total of 22,567 person-years of follow-up.
Calculated adjusted hazards ratios for first cardiovascular hospitalization related to ischemic etiology and reduced ejection fraction.
10-year mortality rate was 98.8%, with 35,966 hospital readmissions recorded.
First cardiovascular hospitalization hazard ratio was 1.36 for ischemic heart failure with P<0.001.
26.8% of recurrent heart failure hospitalizations occurred in the first decile of survival duration.

Structured PICO

What are the predictors of hospitalization and patterns of cardiovascular events over the lifetime of patients newly admitted with heart failure?

Population

8543 newly discharged patients with heart failure (April 1999-March 2001) in the Enhanced Feedback For Effective Cardiac Treatment phase 1 study, mean age 77.4±10.5 years, 51.6% women, 60.7% ischemic etiology, 67.3% HFrEF (LVEF ≤45%).

Outcome

Recurrent hospitalizations, cardiovascular events, and survival over 10-year follow-uphard clinical

In patients newly discharged with heart failure, cardiovascular events cluster in the early postdischarge and prefatal periods, with ischemic etiology being a strong predictor of recurrent hospitalizations.

Cite This Study

Chun et al. (2012) studied this question.

synapsesocial.com/papers/69f69090e405cc4465bc2907 https://doi.org/10.1161/circheartfailure.111.964791

Topics

HFrEF treatment Heart failure Women and heart disease Heart failure hospitalization

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Lifetime Analysis of Hospitalizations and Survival of Patients Newly Admitted With Heart Failure

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Lifetime Analysis of Hospitalizations and Survival of Patients Newly Admitted With Heart Failure

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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