Performance Evaluation of the 2020 European Society of Cardiology 0-hour/1-hour Algorithm Using High-sensitivity Cardiac Troponin I for Non-ST-segment Elevation Acute Coronary Syndrome and Mortality Assessment Based on 1-year Real-world Data

Figures

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  Fig. 1. Study workflow and diagnostic performance of the 2020 ESC 0-hr/1-hr algorithm using hs-cTnI. 1 hr∆ is the hs-cTnI level at 1 hr minus the hs-cTnI level at 0 hr. Parenthetical elements indicate 95% confidence levels. NPV/sensitivity/PPV/specificity were calculated as described in the Methods section. Abbreviations: ESC, European Society of Cardiology; F/U, follow-up; hs-cTnI, high-sensitivity cardiac troponin I; NPV, negative predictive value; NSTE-ACS, non-ST-segment elevation acute coronary syndrome; PPV, positive predictive value; STEMI, ST-segment elevation myocardial infarction.

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  Fig. 2. Kaplan–Meier survival curves with 95% confidence intervals of 30-day overall survival probability of patient subgroups categorized according to the 2020 ESC 0-hr/1-hr algorithm. ****P< 0.001 for the difference between the two subgroups. Colors below the graph correspond to those in the graph. “Patients at risk (N)” indicates the number of patients alive on the day of follow-up, corresponding to that in the above graph. Abbreviations: ESC, European Society of Cardiology; N/A, not applicable.

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  Fig. 3. Box-plot of ED stay durations in patient groups categorized according to the 2020 ESC 0-hr/1-hr algorithm (P<0.001, Kruskal–Wallis with Bonferroni corrections). The number of patients in each group is indicated under the group names. Abbreviations: ED, emergency department; ESC, European Society of Cardiology.