Why the study?
Does a standardized clinical diagnostic algorithm accurately diagnose pulmonary embolism in patients with suspected PE?
Population
750 consecutive patients with suspected pulmonary embolism enrolled in the Prospective Investigative Study…
Comparison
Clinical diagnostic algorithm for PE. vs Pulmonary angiography (reference standard).
Design
Cohort
Authors
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Supports the algorithm's accuracy for PE diagnosis in this cohort; leaves open prospective validation before changing practice.
Does a standardized clinical diagnostic algorithm accurately diagnose pulmonary embolism in patients with suspected PE?
A clinical diagnostic algorithm combining specific symptoms with ECG and radiographic abnormalities demonstrates high sensitivity (84%) and specificity (95%) for diagnosing pulmonary embolism, potentially reducing the need for angiography.
Miniati et al. (1999) studied this question.
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