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May 3, 2026Organic & Biomolecular Chemistry0 citations

Palladium-catalyzed direct amination of N-(quinolin-8-yl)-1H-indole-3-carboxamides

X(Xiaolong Wang (20235)YCYan CaoLWLinqi Wang

Key Points

  • The aim is to develop a method for the direct amination of indoles using palladium catalysts.
  • Utilized palladium as a catalyst for C-H bond cleavage.
  • Employed di-tert-butyldiaziridinone as a nitrogen source.
  • Focused on constructing 2-amino indole skeletons.
  • Successfully demonstrated effective C-H bond cleavage.
  • Achieved high yields of 2-amino indole structures.

Abstract

A palladium-catalyzed C-H bond cleavage and amination of indoles with di-tert-butyldiaziridinone has been developed for the construction of 2-amino indole skeletons. By using di-tertbutyldiaziridinone as the nitrogen source, the reaction...

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Cite This Study

(20235) et al. (2025) studied this question.

synapsesocial.com/papers/69f6e5308071d4f1bdfc5f7ehttps://doi.org/10.1039/d6ob00431h
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