Why the study?
Unstable coronary artery disease carries high morbidity and mortality in diabetic patients, and the best management strategy—including early revascularization—in this high-risk population required further clarification.
Does an early invasive strategy reduce death and myocardial infarction in patients with unstable coronary artery disease with and without diabetes?
Does an early invasive strategy reduce death and myocardial infarction in patients with unstable coronary artery disease with and without diabetes?
An early invasive strategy improves outcomes for both diabetic and nondiabetic patients with unstable coronary artery disease, though diabetes remains a strong independent risk factor for death and myocardial infarction.
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Supports aggressive secondary prevention beyond revascularization for diabetic patients with unstable CAD; reinforces their independent high risk.
Norhammar et al. (2004) studied this question.
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