Synchronization in neuronal cultures

Pascal Monceau; Stéphane Métens; Samuel Bottani

doi:10.1051/epjconf/202636601010

January 1, 2026EPJ Web of ConferencesOpen Access

Synchronization in neuronal cultures

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Key Points

To model the activity behavior of 2D neuronal cultures as neuron coupling changes with varying calcium levels.
Developed a model to describe neuronal activity.
Examined the transition from asynchronous to synchronous activity based on varying calcium concentrations.
Analyzed how changes in calcium levels impact neuronal coupling.
Increased calcium levels lead to a transition from asynchronous to synchronous neuronal activity.
Neurons initially functioned as independent oscillators before forming collective bursts.
Observed a clear relationship between calcium concentration and neuronal synchronization.

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Implication

Examines synchronization in neuronal cultures, suggesting calcium levels influence activity patterns.

Abstract

We have developed a model able to describe the experimentally observed activity behavior of 2D neuronal cultures as the coupling between neurons varies. As [ Ca 2+ ] in the medium increases, a gradual transition occurs from an asynchronous state in which neurons behave as independent oscillators, to a synchronous state where bursts of collective activity appear.

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Cite This Study

Monceau et al. (2026) studied this question.

synapsesocial.com/papers/69f836aa3ed186a739980e55 https://doi.org/10.1051/epjconf/202636601010

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Synchronization in neuronal cultures

Key Points

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Implication

Abstract

Discussion

Cite This Study

Synchronization in neuronal cultures

Key Points

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Implication

Abstract

Discussion

Cite This Study

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