What question did this study set out to answer?

This analysis seeks to identify patient, tumor, and treatment factors associated with long-term arm swelling in breast cancer patients after radiotherapy.

May 4, 2026

Factors associated with arm swelling in patients undergoing surgery and radiotherapy for breast cancer within the FAST-Forward trial nodal sub-study.

View Full Paper

Ask AI

Bookmark

This analysis seeks to identify patient, tumor, and treatment factors associated with long-term arm swelling in breast cancer patients after radiotherapy.
Data from 469 patients randomly assigned to various radiotherapy doses in the FAST-Forward trial were analyzed.
DICOM-RT data were collected prospectively, and logistic regression methods were utilized to identify predictors of arm swelling.
Evaluated factors included axillary surgery, number of positive lymph nodes, and dosimetric parameters.
Axillary surgery was identified as a significant predictor of moderate/marked arm swelling (OR 3.31 [1.08-10.12], p=0.036).
For clinician-reported arm lymphoedema, ALND was a significant predictor (OR 3.67 [1.55-8.69], p=0.003), along with the number of positive lymph nodes (OR 1.08 [1.00-1.18], p=0.049).
No significant correlations were found between dosimetric parameters and long-term arm swelling.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Randomized trial identifies factors linked to long-term arm swelling in breast cancer patients, suggesting treatment adjustments.

Cite This Study

Ravindra et al. (2026) studied this question.

synapsesocial.com/papers/69f837233ed186a7399814bd https://doi.org/10.1016/j.radonc.2026.111547

View Full Paper

Ask AI

Bookmark

Factors associated with arm swelling in patients undergoing surgery and radiotherapy for breast cancer within the FAST-Forward trial nodal sub-study.

Key Points

Discussion

Implication

Cite This Study

Factors associated with arm swelling in patients undergoing surgery and radiotherapy for breast cancer within the FAST-Forward trial nodal sub-study.

Key Points

Discussion

Implication

Cite This Study

Keep reading

Keep reading