Why the study?
Despite advances in hospital management, it remained unclear whether mortality after acute pulmonary embolism had decreased over time.
Have the management strategies and 30-day mortality outcomes for acute pulmonary embolism improved over time?
Population
23,858 adults with acute PE enrolled between 2001 and 2013
Comparison
Temporal trends over time (2001 to 2005 vs 2010 to 2013)
Design
Registry-based temporal trend study
Follow-up
30 days after diagnosis
Authors
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Reassures clinicians on acute PE prognosis; leaves open impact of specific management advances versus temporal trends.
Have the management strategies and 30-day mortality outcomes for acute pulmonary embolism improved over time?
Over a 12-year period, improvements in hospital length of stay and shifts in initial treatment for acute PE were associated with significant reductions in 30-day all-cause and PE-specific mortality.
Jiménez et al. (2016) studied this question.