January 1, 2007European Journal of Endocrinology
Increased preoperative glucose levels are associated with perioperative mortality in patients undergoing noncardiac, nonvascular surgery
Why the study?
Are elevated preoperative glucose levels associated with increased perioperative mortality in patients undergoing noncardiac, nonvascular surgery?
Population
2,868 patients who underwent elective noncardiac, nonvascular surgery at Erasmus MC during 1991-2001. Cases…
Comparison
Preoperative prediabetes or diabetes levels vs Preoperative normal glucose levels (<5.6 mmol/l)
Design
Case-control
Follow-up
30 days
Authors
Discussion
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Member takes
Implication
Preoperative hyperglycemia may flag higher perioperative mortality risk in noncardiac surgery; leaves open whether glucose control improves outcomes.
Structured PICO
Are elevated preoperative glucose levels associated with increased perioperative mortality in patients undergoing noncardiac, nonvascular surgery?
P
Population
2,868 patients (989 cases, 1879 matched controls) who underwent elective noncardiac, nonvascular surgery at Erasmus MC during 1991-2001. Cases were patients who died within 30 days during hospital stay.
I
Intervention
Preoperative prediabetes (glucose 5.6-11.1 mmol/l) or diabetes (glucose ≥11.1 mmol/l) levels
C
Comparator
Preoperative normal glucose levels (<5.6 mmol/l)
O
Outcome
Perioperative mortality (death within 30 days during hospital stay)hard clinical
Preoperative hyperglycemia (both prediabetes and diabetes ranges) is significantly associated with increased 30-day perioperative mortality, including cardiovascular death, in patients undergoing noncardiac, nonvascular surgery.
Cite This Study
Noordzij et al. (2007) studied this question.