Higher levels of psychological distress were independently associated with an increased risk of incident cardiovascular disease, even after accounting for Life's Essential 8 metrics (P=0.011).
Cohort (n=6,410)
Yes
Does psychological distress increase the risk of incident cardiovascular disease independent of Life's Essential 8 metrics in adults without prior CVD?
Higher levels of psychological distress are independently associated with an increased risk of incident cardiovascular disease, suggesting that incorporating psychological distress into cardiovascular health assessments may enhance risk stratification.
p-value: p=0.011
BACKGROUND: Although psychological stress has emerged as an important determinant of cardiovascular disease (CVD) risk, it remains excluded from the recently updated cardiovascular health (CVH) metrics, known as Life's Essential 8 (LE8). This study aimed to examine the association between psychological distress and the incidence of CVD, independent of Life's Essential 8 metrics, in a large Korean adult population. METHODS: This study included 6,410 participants from the Korean Genome and Epidemiology Study Ansan-Ansung cohort, who had no history of CVD and had complete baseline data on psychological distress and Life's Essential 8 cardiovascular health (LE8 CVH) metrics. Psychological distress was assessed using the Psychosocial Wellbeing Index Short Form (PWI-SF). CVD events were identified based on participants' self-reports of physician-diagnosed conditions: myocardial infarction, stroke, coronary artery disease, and congestive heart failure. Cox proportional hazards models were used to examine the association between PWI-SF scores and incident CVD, adjusting for age, sex, residential area, educational attainment, household income, and LE8 CVH metrics. RESULTS: = 0.011). CONCLUSION: These findings suggest that higher levels of psychological distress are independently associated with an increased risk of CVD, even after accounting for established LE8 CVH metrics. Incorporating psychological distress into future CVH assessments may enhance risk stratification and prevention strategies.
Lee et al. (Mon,) conducted a cohort in Cardiovascular disease (n=6,410). Psychological distress was evaluated on Incident cardiovascular disease (myocardial infarction, stroke, coronary artery disease, and congestive heart failure) (p=0.011). Higher levels of psychological distress were independently associated with an increased risk of incident cardiovascular disease, even after accounting for Life's Essential 8 metrics (P=0.011).
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