Why the study?
Does NT-proBNP predict mortality and does carvedilol reduce NT-proBNP levels in patients with severe chronic heart failure?
Does NT-proBNP predict mortality and does carvedilol reduce NT-proBNP levels in patients with severe chronic heart failure?
NT-proBNP is a powerful predictor of all-cause mortality in severe CHF, and its levels are significantly reduced by carvedilol treatment compared to placebo.
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NT-proBNP tertiles stratify mortality risk in severe CHF; confirms its prognostic utility for risk assessment in practice and trials.
Hartmann et al. (2004) studied this question.
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