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The synthesis and characterization of bioconjugates via SN2 reaction shows new derivatives with potential applications.
The synthesis of three novel, valuable bioconjugates obtained by coupling cholesterol bromoacetate with pyridine derivatives via an SN2 reaction was successfully carried out. Each of the products was fully characterized by magnetic nuclear resonance (1H, 13C, APT, 1H−1H COSY, 1H–13C HMBC, 1H–13C HSQC), infrared spectroscopy (IR), and high-resolution mass spectrometry (HRMS).
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Peña-Martínez et al. (2026) studied this question.
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