Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 6, 2026Journal of Drug Research in Ayurvedic SciencesOpen Access

Acute and sub-chronic oral toxicity study of AYUSH MANAS in experimental animals

View Full Paper
Ask AI
Bookmark
Share

Authors

YKY.R. Sanjaya KumarNSN Thamizh SelvamNGN. Sudesh Gaidhani

Discussion

Loading...

Member takes

Overview

Acute oral toxicity study shows AYUSH MANAS is safe in Swiss albino mice, indicating no adverse effects at multiple doses in rats.

Key Points

  • The study aims to evaluate the safety of AYUSH MANAS through acute and repeated-dose oral toxicity assessments.
  • Conducted acute toxicity study with AYUSH MANAS at 1530 mg/kg on Swiss albino mice.
  • Performed 90-day repeated-dose toxicity study with three doses (106, 530, and 1060 mg/kg) on rats.
  • Evaluated clinical signs, behavioral changes, and physical appearance during the experiments, followed by comprehensive organ examinations.
  • No abnormal behavioral activity was observed in mice after acute administration.
  • No pre-terminal deaths occurred in rats over the 90-day study at all doses.
  • Hematological and biochemical examination revealed no significant changes, and histopathological analysis showed no major lesions.

Cite This Study

Kumar et al. (2026) studied this question.

synapsesocial.com/papers/69fa8eac04f884e66b530f5ahttps://doi.org/10.4103/jdras.jdras_346_25
View Full Paper
Ask AI
Bookmark
Share