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The aim is to develop a 3D-printed theranostic hydrogel for multifunctional wound management.

May 6, 2026GelsOpen Access

Vat Photopolymerization-Fabricated Theranostic Hydrogels for Smart Wound Management

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3D-printed theranostic hydrogels enhance wound management, suggesting improved diagnostics and therapy integration.

The aim is to develop a 3D-printed theranostic hydrogel for multifunctional wound management.
Developed a hydrogel using vat photopolymerization with poly(acrylamide-co-hydroxyethyl acrylate) and carboxymethyl cellulose.
Incorporated bromocresol purple for diagnostic indications and graphene oxide for drug delivery.
Conducted tests on swelling capacity and pH responsiveness of the hydrogel.
Hydrogel showed over 600% swelling capacity for wound exudate absorption.
Cumulative release of levofloxacin was 92.63% at pH 8, demonstrating enhanced therapy under infection conditions.
Differentiated healthy healing skin from infected conditions based on colorimetric pH responses.

Tiston et al. (2026) studied this question.

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