ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae

Adam Sidi Mabrouk; Jamie S. Depelteau; Chiara Foini; Annabel Kempff; Sebastiaan Jonker; Susanne Brenzinger; Ronald Limpens; Manuel Majrouh; Annemarie H. Meijer; Ariane Briegel

doi:10.1128/spectrum.03565-25

May 4, 2026Microbiology SpectrumOpen Access

ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae

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Key Points

The study aims to explore the effects of ICP1 bacteriophage on Vibrio cholerae colonization in zebrafish larvae.
Conducted phage treatment on zebrafish larvae
Analyzed intestinal colonization by Vibrio cholerae
Examined phage-bacteria interactions
Phage treatment significantly reduced colonization levels of Vibrio cholerae in the zebrafish intestine
Demonstrated important phage-bacteria dynamics affecting pathogen presence

Implication

Phage treatment reduces colonization of zebrafish larvae by Vibrio cholerae, indicating critical phage-bacteria interactions.

Abstract

N16961-dsRED by ICP1, underscoring the role of phage-bacteria dynamics in shaping pathogen colonization within the zebrafish larval host. IMPORTANCE: during colonization.

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Cite This Study

Mabrouk et al. (2026) studied this question.

synapsesocial.com/papers/69faa1eb04f884e66b53299e https://doi.org/10.1128/spectrum.03565-25

View Full Paper

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ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae

Key Points

Implication

Abstract

Discussion

Cite This Study

ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae

Key Points

Implication

Abstract

Discussion

Cite This Study

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