Biotransformation of progesterone by Aspergillus welwitschiae CCMB 674 yields a novel metabolite 11α,21-dihydroxyprogesterone, alongside three known compounds | Synapse
May 6, 2026Open Access
Biotransformation of progesterone by Aspergillus welwitschiae CCMB 674 yields a novel metabolite 11α,21-dihydroxyprogesterone, alongside three known compounds
Key Points
The research focuses on the biotransformation of progesterone by Aspergillus welwitschiae.
The biotransformation process was conducted over 168 hours.
The study analyzed the yield of a novel metabolite and three known compounds.
A novel metabolite, 11α,21-dihydroxyprogesterone, was produced.
Aspergillus welwitschiae showed potential as a biocatalyst for selective steroid hydroxylation.
Abstract
after 168 h. These findings highlight A. welwitschiae as a promising biocatalyst for selective steroid hydroxylation.