Effects of Exercise Training on Left Ventricular Function and Peripheral Resistance in Patients With Chronic Heart Failure
Why the study?
Does exercise training improve left ventricular function and central hemodynamics in men with stable chronic heart failure?
Population
73 men aged 70 years or younger with stable chronic heart failure and LV ejection fraction of approximately…
Comparison
2 weeks of in-hospital ergometer exercise for 10… vs No intervention (control group).
Design
RCT, Randomly assigned
Follow-up
6 months
Authors
Discussion
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Member takes
Implication
Supports exercise training in stable HF management; reinforces its benefits on central hemodynamics and LV remodeling.
Structured PICO
Does exercise training improve left ventricular function and central hemodynamics in men with stable chronic heart failure?
P
Population
73 men aged 70 years or younger with stable chronic heart failure and LV ejection fraction of approximately 0.27.
I
Intervention
2 weeks of in-hospital ergometer exercise for 10 minutes 4 to 6 times per day, followed by 6 months of home-based ergometer exercise training for 20 minutes per day at 70% of peak oxygen uptake.
C
Comparator
No intervention (control group).
O
Outcome
Ergospirometry with measurement of central hemodynamics by thermodilution at rest and during exercise; echocardiographic determination of LV diameters and volumes, at baseline and 6-month follow-up.surrogate
In patients with stable chronic heart failure, exercise training significantly improves central hemodynamics, increases stroke volume, and reduces cardiomegaly.
Cite This Study
Rainer Hambrecht (2000) studied this question.