Quest for a Unifying Diagnosis: Felty Syndrome?

Felty syndrome is a rare seropositive rheumatoid arthritis (RA), splenomegaly, and absolute neutropenia [1] occurring in less than 1% of patients with RA [2]. As the disease itself is asymptomatic, patients usually present with acute infection superimposed on a long-standing, erosive RA diagnosis [2]. Infective endocarditis is one of the most common life-threatening infectious syndromes [2]. We describe a rare case of infective endocarditis in a patient with a diagnosis of Felty syndrome.