Key result
A 53-year-old woman with recurrent deep vein thrombosis and ischemic stroke was diagnosed with non-bacterial thrombotic endocarditis secondary to an underlying lung adenocarcinoma.
Why the study?
Non-bacterial thrombotic endocarditis is difficult to diagnose and often requires a high index of suspicion, especially in patients with thrombotic history.
Case Report (n=1)
No
Highlights non-bacterial thrombotic endocarditis as a potential manifestation of underlying malignancy such as lung cancer, requiring a high index of suspicion.
Hypothesis-generating for occult malignancy in nonbacterial thrombotic endocarditis; prospective studies needed before changing practice.
Non-bacterial thrombotic endocarditis (NBTE) is characterized by vegetations on cardiac valves consisting of fibrin and platelet aggregates that are devoid of inflammation or bacteria. Diagnosis is often challenging and is aided by a high index of suspicion. These factors are reflected by the case of a 53 year old woman with a history of recurrent idiopathic deep vein thrombosis (DVT) prior to presentation at our institution to which she was admitted because of right upper extremity numbness and weakness.
No takes yet. Share an insight, caveat, or question.
Sandhya Venugopal (2020) conducted a case report in Non-bacterial thrombotic endocarditis (NBTE) and lung adenocarcinoma (n=1). Systemic anticoagulation (heparin) was evaluated. A 53-year-old woman with recurrent deep vein thrombosis and ischemic stroke was diagnosed with non-bacterial thrombotic endocarditis secondary to an underlying lung adenocarcinoma.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: