What type of study is this?

This is a In Vitro Study study.

What question did this study set out to answer?

To assess the phytochemical composition, biological properties, and metabolomic profile of cymbopogon citratus leaf extract.

May 7, 2026Journal of ChemistryOpen Access

Biological Activities and Metabolomic Profiling of Cymbopogon citratus (DC.) Stapf Leaf Extract Using LC–MS Analysis

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Authors

NGNidhi GuptaChandigarh University NSNitin SharmaChandigarh University VPVivek PanwarChitkara University

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Implication

Metabolomic profiling shows antioxidant activity and low cytotoxicity in cymbopogon citratus extract, indicating potential for metabolic health applications.

Key Points

To assess the phytochemical composition, biological properties, and metabolomic profile of cymbopogon citratus leaf extract.
Utilized liquid chromatography–mass spectrometry (LC–MS) for metabolomic analysis.
Assessed antioxidant activity through DPPH radical scavenging and ferric reducing antioxidant power (FRAP).
Evaluated in vitro antidiabetic effects by measuring inhibition of α-amylase, α-glucosidase, and DPP-IV.
Conducted cytotoxicity testing using L6 myoblasts.
Extract demonstrated significant antioxidant activity with an IC 50 of 12.29 μg/mL for DPPH.
Showed potent antidiabetic activity by inhibiting α-amylase with an IC 50 of 6.34 μg/mL.
Revealed low cytotoxicity at tested concentrations in L6 myoblasts.
Identified various bioactive metabolites including phenolic acids and triterpenes.

Cite This Study

Gupta et al. (2026) studied this question.

synapsesocial.com/papers/69fbe382164b5133a91a2c70 https://doi.org/10.1155/joch/5568823

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Implication

Metabolomic profiling shows antioxidant activity and low cytotoxicity in cymbopogon citratus extract, indicating potential for metabolic health applications.

Biological Activities and Metabolomic Profiling of Cymbopogon citratus (DC.) Stapf Leaf Extract Using LC–MS Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Biological Activities and Metabolomic Profiling of Cymbopogon citratus (DC.) Stapf Leaf Extract Using LC–MS Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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