Key result
Cymbopogon citratus extract lowers lipids and glucose in rats, potentially via APJ protein binding.
Why the study?
The anti-obesity potential and mechanisms of Cymbopogon citratus methanolic extract were not fully elucidated in preclinical models.
Does Cymbopogon citratus methanolic extract reduce lipids and glucose in HCHFD rats?
Population
HCHFD rats and molecular docking models
Comparison
Cymbopogon citratus methanolic extract vs control
Design
Preclinical in vivo and molecular docking study
Authors
Loading...
Should not yet change practice; leaves open whether APJ-targeted flavones merit human trials for obesity.
Does Cymbopogon citratus methanolic extract reduce lipids and glucose in HCHFD rats?
Cymbopogon citratus methanolic extract demonstrates potential hypolipidemic and anti-obesity properties in a preclinical rat model.
Aly et al. (2024) studied this question. Cymbopogon citratus methanolic extract reduced lipids and glucose in high-fat diet rats, demonstrating anti-obesity effects potentially mediated by flavone binding to the APJ protein.