Formulation of Coreopsis tinctoria gels improves antioxidant activity in skin, suggesting potential for photoaging treatment.
drug release from CTGs followed the Korsmeyer-Peppas model. Compared with the liquid formulation, CTGs significantly prolonged skin retention time and improved skin adhesion within 8 h. CTGs attenuated UVB-induced dermal damage, increased SOD activity and hydroxyproline (Hyp) content, and reduced MDA content and tyrosinase (Tyr) activity, indicating strong antioxidant and tyrosinase inhibitory activity. CTGs represent a promising dermal delivery strategy for ameliorating skin photoaging and abnormal pigmentation.
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Du et al. (2026) studied this question.
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