Why the study?
What are the determinants of increased carotid intima-media thickness in obese children?
Population
104 obese children, 93 nonobese children for blood parameters, and 23 control children for IMT measurement.
Design
Cross-sectional
Authors
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Adiponectin may mark early vascular changes in obese youth; leaves open causal role and need for longitudinal validation before practice change.
What are the determinants of increased carotid intima-media thickness in obese children?
Adiponectin levels are independently associated with early atherosclerosis (increased IMT) in obese children, more so than conventional cardiovascular risk factors.
Beauloye et al. (2007) studied this question.
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