Key result
Men in the highest quintile of plasma adiponectin had a significantly lower risk of MI compared to the lowest quintile (RR 0.39; 95% CI 0.23-0.64; P<.001).
Why the study?
Are high plasma adiponectin levels associated with a reduced risk of myocardial infarction in men?
Population
798 men aged 40 to 75 years who were free of diagnosed cardiovascular disease at the time of blood draw…
Comparison
Highest quintile of plasma adiponectin levels vs Lowest quintile of plasma adiponectin levels
Design
Case-control
Follow-up
6 years
Authors
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Supports adiponectin assessment for MI risk in men; leaves open causality and need for prospective trials.
Case-Control (n=798)
Are high plasma adiponectin levels associated with a reduced risk of myocardial infarction in men?
Effect estimate: RR 0.39 (95% CI 0.23-0.64)
p-value: p=<.001
High plasma adiponectin concentrations are independently associated with a lower risk of myocardial infarction in men.
Tobias Pischon (2004) conducted a case-control in Myocardial Infarction (n=798). High plasma adiponectin concentrations (highest quintile) vs. Lowest quintile of adiponectin levels was evaluated on Incidence of nonfatal MI and fatal coronary heart disease (RR 0.39, 95% CI 0.23-0.64, p=<.001). Men in the highest quintile of plasma adiponectin had a significantly lower risk of MI compared to the lowest quintile (RR 0.39; 95% CI 0.23-0.64; P<.001).
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