Key result
Men in the highest quintile of plasma adiponectin had a significantly lower risk of MI compared to the lowest quintile (RR 0.39; 95% CI 0.23-0.64; P<.001).
Why the study?
Are high plasma adiponectin levels associated with a reduced risk of myocardial infarction in men?
Case-Control (n=798)
Are high plasma adiponectin levels associated with a reduced risk of myocardial infarction in men?
Effect estimate: RR 0.39 (95% CI 0.23-0.64)
p-value: p=<.001
High plasma adiponectin concentrations are independently associated with a lower risk of myocardial infarction in men.
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Supports adiponectin assessment for MI risk in men; leaves open causality and need for prospective trials.
Tobias Pischon (2004) conducted a case-control in Myocardial Infarction (n=798). High plasma adiponectin concentrations (highest quintile) vs. Lowest quintile of adiponectin levels was evaluated on Incidence of nonfatal MI and fatal coronary heart disease (RR 0.39, 95% CI 0.23-0.64, p=<.001). Men in the highest quintile of plasma adiponectin had a significantly lower risk of MI compared to the lowest quintile (RR 0.39; 95% CI 0.23-0.64; P<.001).
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