Left ventricular hypertrophy and function in high, normal, and low-renin forms of essential hypertension.
Why the study?
Does renin profile status determine the degree of left ventricular hypertrophy and dysfunction in patients with essential hypertension?
Population
118 hypertensive patients off medication, categorized into high-renin, normal-renin, and low-renin groups.
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
LVH in essential hypertension tracks BP severity irrespective of renin status; leaves open whether renin profiling refines LVH risk stratification or therapy.
Structured PICO
Does renin profile status determine the degree of left ventricular hypertrophy and dysfunction in patients with essential hypertension?
P
Population
118 hypertensive patients off medication, categorized into high-renin (n=19), normal-renin (n=79), and low-renin (n=20) groups.
C
Comparator
Comparison between high-renin, normal-renin, and low-renin profiles.
O
Outcome
Left ventricular hypertrophy (assessed by LV mass index and relative wall thickness) and LV dysfunction (assessed by LV fractional systolic shortening) measured by quantitative echocardiography.surrogate
The degree of left ventricular hypertrophy in essential hypertension is proportional to the severity of blood pressure elevation rather than the patient's renin profile.
Cite This Study
Devereux et al. (1982) studied this question.