Key result
Early IV diuretics in decompensated HF linked to shorter ED stays under 6 hours.
Why the study?
Earlier administration of loop diuretics in decompensated heart failure may reduce morbidity and mortality, prompting evaluation of real-world timing and 30-day readmissions.
Does early administration of intravenous diuretics (within 60 minutes) reduce emergency department stay and readmission in patients with decompensated heart failure?
Cohort (n=361)
No
Does early administration of intravenous diuretics (within 60 minutes) reduce emergency department stay and readmission in patients with decompensated heart failure?
p-value: p=<0.003
Early administration of intravenous diuretics within 60 minutes of emergency department arrival for decompensated heart failure is associated with shorter emergency department stays.
Prompt diuretic use may shorten ED stays in acute HF; leaves open effects on 30-day readmissions pending randomized confirmation.**[[1]](https://ijcscardiol.
Introduction: Evidence suggests that patients with decompensated heart failure who receive loop diuretics earlier experience reduced morbidity and mortality rates. Objectives: To determine the time from admission to administration of the first dose of diuretics in patients with heart failure and to evaluate the risk of readmission within 30 days after hospital discharge. Methods: A prospective and retrospective cohort study of patients with decompensated heart failure treated in a cardiac emergency department between December 2018 and June 2020 was [...]
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Rosa et al. (2026) conducted a cohort in Decompensated heart failure (n=361). Early diuretic administration (within 60 minutes) vs. Diuretic administration after 60 minutes was evaluated on Emergency department stay of less than 6 hours (p=<0.003). Early administration of diuretics within 60 minutes of admission in patients with decompensated heart failure was significantly associated with a shorter emergency department stay of less than 6 hours.
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