Anti-Inflammatory and Antioxidant Effects of Pilea anisophylla Wedd. (Urticaceae) Extract via the Regulation of the NF-κB Pathway

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Key Points

The study aims to evaluate the anti-inflammatory and antioxidant effects of Pilea anisophylla extract through the modulation of the NF-κB pathway.
Evaluated the extract's effects on inflammation and oxidative stress in cultured cells.
Analyzed the modulation of the NF-κB pathway as a mechanism of action.
Utilized biochemical assays to assess antioxidant activity.
Pilea anisophylla extract significantly reduced NF-κB activation (p<0.01).
Showed improved antioxidant capabilities with a 30% increase in cellular antioxidant activity (p<0.05).
Demonstrated a 25% reduction in inflammatory cytokine levels (p<0.01).

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Demonstrates anti-inflammatory and antioxidant effects in cell models, suggesting potential health benefits of Pilea anisophylla extract.

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Jeong et al. (2026) studied this question.

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