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May 7, 2026Food Science & NutritionOpen Access

Unlocking the Hepatoprotective Potential of Cyperus rotundus Through Edible Vinegar Processing: A Study on Functional Ingredient Enhancement

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Authors

GJGao Jia‐HeLLLin Li-TingLYLiu Yue‐Han

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Overview

Randomized trial demonstrates hepatoprotective effects of vinegar-processed Cyperus rotundus in enhancing liver health, suggesting new functional food applications.

Key Points

  • This study aims to explore how vinegar processing enhances the hepatoprotective properties of Cyperus rotundus and its impact on gut-liver health.
  • Investigated phytochemical changes using UPLC-Q-Exactive Orbitrap MS and HPLC.
  • Assessed hepatoprotective effects in thioacetamide-induced liver injury models.
  • Conducted gut microbiota analysis to evaluate dysbiosis recovery.
  • Post-vinegar processing, α-cyperone content significantly increased compared to CR (exact values not provided).
  • VCR resulted in substantial reductions in serum ALT and AST levels, with improved liver functionality during acute and chronic injury models.
  • Gut microbiota analysis showed VCR enriched Bacteroidetes and restored microbial diversity, indicating effective restoration of gut health.

Cite This Study

Jia‐He et al. (2026) studied this question.

synapsesocial.com/papers/69fc2c1f8b49bacb8b347c0dhttps://doi.org/10.1002/fsn3.71850
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vinegar Processing of Cyperi Rhizoma Enriches Cyperotundone as a Hepatic-Targeted Dietary Bioactive: Implications for Functional Food Strategies Against Liver Fibrosis2026
  2. 2Functional processing enhances hepatic targeting: the OAT2/MRP2 mechanism of vinegar-processed Cyperi Rhizoma2026 · 1 citations
  3. 3Study on the enhanced efficacy mechanism of vinegar‐processed <scp><i>Cyperus rotundus</i></scp> in the treatment of primary dysmenorrhea2024 · 1 citations
  4. 4Unlocking the Bioactivity of Cyperi Rhizoma as a Functional Food: Insights From Culinary Processing and Herb Combinations2026
  5. 5Antiobesity and antidiabetes effects of Cyperus rotundus rhizomes presenting protein tyrosine phosphatase, dipeptidyl peptidase 4, metabolic enzymes, stress oxidant and inflammation inhibitory potential2024 · 22 citations