PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
August 5, 2026NutrientsOpen Access

Vinegar Processing of Cyperi Rhizoma Enriches Cyperotundone as a Hepatic-Targeted Dietary Bioactive: Implications for Functional Food Strategies Against Liver Fibrosis

View Full Paper
Ask AI
Bookmark
Share

Authors

GXGui XuSZShuo ZhangJTJiafei Tang

Discussion

Loading...

Member takes

Overview

Randomized trial demonstrates enhanced anti-fibrotic effects of vinegar-processed Cyperi Rhizoma, indicating its potential in functional foods.

Key Points

  • The research aims to explore how vinegar processing of Cyperi Rhizoma enhances its bioactive properties against liver fibrosis.
  • Investigated phytochemical transformation and anti-fibrotic effects of vinegar-processed Cyperi Rhizoma.
  • Conducted chemical analysis and hepatic distribution assessments in a CCl4-induced mouse liver fibrosis model.
  • Evaluated cyperotundone enrichment and its contribution to bioactivity.
  • Vinegar processing elevated cyperotundone content by 1.35-fold and enhanced hepatic distribution compared to unprocessed Cyperi Rhizoma.
  • Vinegar-processed Cyperi Rhizoma showed superior anti-fibrotic efficacy in reducing serum transaminases and fibrotic biomarkers.
  • Cyperotundone significantly suppressed the TGF-β/α-SMA/COL-1 signaling pathway, highlighting its role as a key bioactive component.

Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/6a72e802226790f3706577behttps://doi.org/10.3390/nu18152509
View Full Paper
Ask AI
Bookmark
Share