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Review current morphologic and compositional magnetic resonance (MR) imaging techniques used to evaluate knee articular cartilage lesions and monitor therapeutic interventions.

January 1, 2011RadiographicsOpen Access

Articular Cartilage in the Knee: Current MR Imaging Techniques and Applications in Clinical Practice and Research

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Authors

MCM.D. CremaInstitut National du Sport, de l'Expertise et de la Performance FRFrank W. RoemerBoston University MMMonica MarraBoston University

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Implication

Review outlines morphologic and compositional MR imaging techniques for knee cartilage, highlighting noninvasive methods for detecting damage and monitoring therapeutic response.

Key Points

Review current morphologic and compositional magnetic resonance (MR) imaging techniques used to evaluate knee articular cartilage lesions and monitor therapeutic interventions.
Classified knee cartilage MR imaging approaches into structural/morphologic and biochemical/compositional modalities.
Assessed standard, fast, and three-dimensional spin-echo and gradient-recalled echo sequences for structural lesion assessment.
Evaluated quantitative matrix techniques including T2 mapping, dGEMRIC, T1ρ imaging, sodium imaging, and diffusion-weighted imaging.
Morphologic sequences enable semiquantitative and quantitative identification of macroscopic structural defects in articular cartilage.
Compositional techniques noninvasively assess the collagen network and proteoglycan content of the cartilage matrix, detecting biochemical changes before morphological breakdown.
Integrating structural and compositional sequences across different magnetic field strengths improves the monitoring of both pharmacologic and surgical treatments.

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Crema et al. (2011) studied this question.

synapsesocial.com/papers/69fcbae74f95092fbe78f9b4 https://doi.org/10.1148/rg.311105084

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Implication

Review outlines morphologic and compositional MR imaging techniques for knee cartilage, highlighting noninvasive methods for detecting damage and monitoring therapeutic response.

Articular Cartilage in the Knee: Current MR Imaging Techniques and Applications in Clinical Practice and Research

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Key Points

Cite This Study

Articular Cartilage in the Knee: Current MR Imaging Techniques and Applications in Clinical Practice and Research

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Implication

Key Points

Cite This Study

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