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October 24, 2000Proceedings of the National Academy of Sciences

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

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Authors

XDXue-Liang DuDEDiane EdelsteinLRLuciano Rossetti

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Du et al. (2000) studied this question.

synapsesocial.com/papers/69fcc34eb05178e6bafa3a8ahttps://doi.org/10.1073/pnas.97.22.12222
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  1. 1Definition of the carbohydrate response element of the rat S14 gene. Context of the CACGTG motif determines the specificity of carbohydrate regulation.1994 · 111 citations
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  4. 4Role of the glucosamine pathway in fat-induced insulin resistance.1997 · 327 citations
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