Home exposure to moisture and mold is associated with poorer asthma control in children: CHAMPIASTHMA study

Background: Deleterious indoor environment is a risk factor for poor asthma control in children. Objective: We assessed the association between exposure to moisture and/or mold (EMM) and asthma control in children. Methods: The CHAMPIASTHMA study is a multicenter cross-sectional observational study. Children with recurrent wheeze/asthma aged 1 to 17 years were stratified by EMM, as assessed by a standardized questionnaire administered to their parents. The primary outcome was asthma control according to Global Initiative on Asthma guidelines. Secondary outcomes were: control according to asthma control test or pediatric asthma control test score, exacerbations (unscheduled visits, oral corticosteroid receipt, and hospitalization), asthma treatment step, and mold sensitization. Clinical trial registration: NCT04918394. Conclusion: The CHAMPIASTHMA study highlights that EMM is associated with poorer disease control and asthma outcomes in children. The search for EMM during scheduled visits should be systematic, especially in cases of uncontrolled asthma.