Why the study?
The diversity and clinical significance of the morphologic expression of hypertrophic cardiomyopathy had not been fully defined within its broad disease spectrum.
Population
600 patients with hypertrophic cardiomyopathy consecutively studied at two referral centers
Design
Two-center observational study
Authors
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Encourages comprehensive LV wall thickness assessment in HCM; leaves open independent prognostic value of specific hypertrophy distributions.
Two-dimensional echocardiography demonstrates that left ventricular hypertrophy in hypertrophic cardiomyopathy is highly heterogeneous and characteristically asymmetric, with no single typical morphologic expression.
Klues et al. (1995) studied this question.
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