Population
Genetic mouse models and humans with cell-cell junction-based diseases
Design
Review
Authors
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Anchoring junction defects may contribute to conduction disease; leaves open mechanistic validation and targeted therapies.
Anchoring cell junctions play an integral role alongside gap junctions in maintaining electro-mechanical coupling in the cardiac conduction system, with defects leading to conduction impairments.
Mezzano et al. (2014) studied this question.
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