Clinical Correlates and Heritability of Flow-Mediated Dilation in the Community
Population
2883 Framingham Study participants, 52.9% women, mean age 61 years.
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
FMD associations with risk factors and modest heritability are hypothesis-generating; longitudinal studies needed before clinical adoption.
Structured PICO
P
Population
2883 Framingham Study participants, 52.9% women, mean age 61 years.
O
Outcome
Brachial artery flow-mediated dilation (FMD), expressed as percent (FMD%) and actual dilationsurrogate
In a community-based sample, endothelial function measured by FMD was modestly heritable and associated with traditional cardiovascular risk factors.
Cite This Study
Benjamin et al. (2004) studied this question.