Prognostic value of serum creatinine and effect of treatment of hypertension on renal function. Results from the hypertension detection and follow-up program. The Hypertension Detection and Follow-up Program Cooperative Group.
Why the study?
Does stepped care compared to referred care reduce the decline of renal function and mortality in persons with hypertension?
Population
10,940 persons with hypertension in a community-based setting
Comparison
Stepped care vs Referred care
Design
RCT, Randomized to one of two treatment groups
Follow-up
5 years
Authors
Discussion
Loading...
Member takes
Implication
Stepped care may preserve renal function in hypertensive patients with mild impairment; extends RCT evidence for intensive BP control in early CKD.
Structured PICO
Does stepped care compared to referred care reduce the decline of renal function and mortality in persons with hypertension?
P
Population
10,940 persons with hypertension in a community-based setting
I
Intervention
Stepped care (aggressive treatment of hypertension)
C
Comparator
Referred care
O
Outcome
All-cause mortalityhard clinical
Aggressive stepped-care treatment of hypertension significantly reduces the decline in renal function compared to referred care, particularly in patients with mild baseline renal impairment.
Cite This Study
Shulman et al. (1989) studied this question.