AAV9-mediated expression of Cre provides a rapid and efficient method for conditional cardiac gene knockout in adult mice without the adverse side effects of traditional systems.
No takes yet. Share an insight, caveat, or question.
Offers tamoxifen-free conditional knockout in adult mouse cardiomyocytes; extends preclinical genetic tools while leaving clinical translation open.
Werfel et al. (2014) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: