Why the study?
Is the production of IFN-gamma by T lymphocytes altered in patients with unstable angina compared to stable angina?
Is the production of IFN-gamma by T lymphocytes altered in patients with unstable angina compared to stable angina?
Unstable angina is characterized by a perturbation of the T-cell repertoire with a bias toward IFN-gamma production by CD4+CD28(null) T cells, suggesting an immune-mediated mechanism in acute coronary syndromes.
No takes yet. Share an insight, caveat, or question.
Association supports immune mechanisms in unstable angina; hypothesis-generating and should not yet change practice.
Liuzzo et al. (1999) studied this question.
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