Key result
Pharmacological BP and HR control remains mandatory to slow progression and prevent rupture in aortic syndromes.
Why the study?
Drug therapy is mandatory across acute and chronic aortic syndromes, warranting a review of therapeutic goals, medications, evidence, lifestyle modifications, and imaging follow-up recommendations.
This review highlights the critical role of optimal medical therapy, particularly beta-blockers, strict blood pressure control, and statins, in the acute and long-term management of aortic syndromes.
Requires BP and HR control across aortic syndromes; leaves open optimal agents and targets pending higher-quality trials.
Drug therapy is a mandatory component of the treatment of patients with acute and chronic aortic syndromes, regardless of the chosen therapeutic approach (surgical, endovascular, or conservative). In the acute phase, it aims to control pain, heart rate, and arterial blood pressure, while in the long-term it seeks to slow disease progression and potentially prevent aortic rupture. This review focuses on the therapeutic goals in aortic diseases, the medications used, and the evidence currently available. Attention is also given to the importance of lifestyle modifi cations, as well as recommendations for follow-up using various imaging modalities.
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Dimitrova et al. (2026) conducted a review in Aortic disease. Pharmacological therapy was evaluated. Pharmacological therapy, primarily strict blood pressure and heart rate control, is a mandatory component in managing acute and chronic aortic syndromes to slow disease progression and prevent rupture.
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