Key result
Intersectional analysis links high school-educated non-Hispanic White males to ~56% higher stroke incidence than average.
Why the study?
Disparities in stroke risk are well documented, but prior research has mostly examined race/ethnicity, sex, and socioeconomic status independently rather than jointly.
How does the intersection of race/ethnicity, sex, and educational attainment influence stroke risk in a population-based cohort?
Population
3,401 first-ever ischemic strokes in south Texas, USA
Comparison
Intersectional subgroups defined by race/ethnicity, sex, and education
Design
Population-based observational study
Authors
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Hypothesis-generating for intersectional stroke incidence disparities; prospective trials needed before clinical adoption.
Observational (n=3,401)
How does the intersection of race/ethnicity, sex, and educational attainment influence stroke risk in a population-based cohort?
Effect estimate: Rate ratio 1.56 (95% CI 1.30-1.88)
Stroke disparities are significantly shaped by the intersection of multiple social identities (race/ethnicity, sex, and education), suggesting that interventions targeting a single dimension may be insufficient.
Lisabeth et al. (2026) conducted an observational in Ischemic stroke (n=3,401). Intersection of race/ethnicity, sex, and educational attainment vs. Across-group average was evaluated on Stroke incidence (Rate ratio 1.56, 95% CI 1.30-1.88). The intersection of race/ethnicity, sex, and education accounted for 66% of variance in stroke incidence, with non-Hispanic White males with HS education having 1.56 times higher rates than average.
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