N-Terminal Pro-Brain Natriuretic Peptide on Admission Has Prognostic Value Across the Whole Spectrum of Acute Coronary Syndromes
Why the study?
Does NT-proBNP measurement on admission predict 30-day mortality in patients with acute coronary syndromes?
Population
1756 patients with acute coronary syndromes (ACS) and ECG evidence of myocardial ischemia
Comparison
Measurement of N-terminal pro-brain natriuretic… vs Lowest quartile of NT-proBNP
Design
Cohort
Follow-up
30 days
Authors
Discussion
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Member takes
Implication
NT-proBNP on admission may aid risk stratification in ACS; leaves open whether measurement changes management or outcomes.
Structured PICO
Does NT-proBNP measurement on admission predict 30-day mortality in patients with acute coronary syndromes?
P
Population
1756 patients with acute coronary syndromes (ACS) and ECG evidence of myocardial ischemia
I
Intervention
Measurement of N-terminal pro-brain natriuretic peptide (NT-proBNP) on admission (median 3 hours after symptom onset)
C
Comparator
Lowest quartile of NT-proBNP
O
Outcome
Death at 30 dayshard clinical
NT-proBNP measured on admission is a strong, independent predictor of 30-day mortality and severe heart failure across the spectrum of acute coronary syndromes.
Cite This Study
Galvani et al. (2004) studied this question.